Former YouTube boss Susan Wojcicki has passed away after two years of living with lung cancer.

The news concerning the ex-YouTube chief executive—and also one of Google’s earliest employees—was confirmed this weekend by Dennis Troper, Wojcicki’s husband, and Sundar Pichai, the CEO of Google and its parent company, Alphabet.

“It is with profound sadness that I share the news of Susan Wojcicki passing. My beloved wife of 26 years and mother to our five children left us today after 2 years of living with non small cell lung cancer,” wrote Troper in a Facebook post.

“Her impact on our family and the world was immeasurable. We are heartbroken, but grateful for the time we had with her.”

On X, formerly known as Twitter, Pichai said: “Unbelievably saddened by the loss of my dear friend @SusanWojcicki after two years of living with cancer.

“She is as core to the history of Google as anyone, and it’s hard to imagine the world without her.

“She was an incredible person, leader and friend who had a tremendous impact on the world and I’m one of countless Googlers who is better for knowing her.

“We will miss her dearly. Our thoughts with her family. RIP Susan.”

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Wojcicki’s association with Google began in 1998, when she rented out her home’s garage in Menlo Park, California, to Google founders Larry Page and Sergey Brin for $1,700 a month.

Her 15-year stint at Google proper started a year later, in 1999. While at Google, she led teams across consumer products and helped build its ad business.

In 2014, Wojcicki became the chief executive of YouTube, a now household name which Google bought in 2006.

In February last year, it was announced that Wojcicki would step down from YouTube’s helm after nearly ten years to focus on personal projects, health, and family.

In an email sent to Google and Alphabet employees commemorating Wojcicki’s life and career, Pichai wrote: “Over the last two years, even as she dealt with great personal difficulties, Susan devoted herself to making the world better through her philanthropy, including supporting research for the disease that ultimately took her life.

“I know that was very meaningful to her and I’m so glad she took the time to do it.”